45 days in Italy Itinerary

45 days in Italy Itinerary

Created using Inspirock Italy trip planner
Make it your trip
1
Milan
— 3 nights
Drive
2
Venice
— 4 nights
Drive
3
Cinque Terre
— 5 nights
Drive
4
Florence
— 5 nights
Drive
5
Volterra
— 3 nights
Drive
6
Siena
— 3 nights
Drive
7
Montalcino
— 2 nights
Drive
8
Pienza
— 2 nights
Drive
9
Montepulciano
— 3 nights
Drive
10
Assisi
— 2 nights
Drive
11
Orvieto
— 3 nights
Drive
12
Rome
— 5 nights
Train
13
Sorrento
— 4 nights

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Milan — 3 nights

Fashion Capital of World

In many ways the most modern of Italian cities, Milan is a busy, elegant metropolis with an impressive list of grand palaces, fine churches, and important museums.
Discover out-of-the-way places like Villa Necchi Campiglio and Gallerie d’Italia. And it doesn't end there: pause for some serene contemplation at Duomo di Milano, contemplate in the serene atmosphere at Chiesa di San Cristoforo sul Naviglio, steep yourself in history at Abbazia di Chiaravalle, and make a trip to Galleria Vittorio Emanuele II.

To see photos, more things to do, where to stay, and other tourist information, refer to the Milan trip itinerary planning app.

If you are flying in from Mexico, the closest major aiports are Malpensa International Airport, Milano Linate Airport and Milan Bergamo Airport. In April, daytime highs in Milan are 22°C, while nighttime lows are 9°C. Finish up your sightseeing early on the 4th (Mon) so you can go by car to Venice.
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Historic Sites · Museums · Childrens Museums · Shopping
Find places to stay Apr 1 — 4:

Venice — 4 nights

City of Romance

Virtually unchanged for the last six centuries, Venice is actually a group of islands made famous by a series of canals, bridges, monuments, piazzas, and narrow pedestrian lanes.
You'll discover tucked-away gems like Basilica di Santa Maria Gloriosa dei Frari and Natural History Museum. You'll find plenty of places to visit near Venice: Padua (Centro Storico di Padova, Padua Botanical Garden - World Heritage Site, &more). Next up on the itinerary: explore the activities along Canal Grande, see the interesting displays at Doge's Palace, wander the streets of Dorsoduro, and pause for some serene contemplation at Basilica di Santa Maria della Salute.

For more things to do, where to stay, reviews, and other tourist information, go to the Venice online road trip planner.

Traveling by car from Milan to Venice takes 3 hours. Alternatively, you can take a train; or take a bus. In April, daily temperatures in Venice can reach 21°C, while at night they dip to 11°C. Wrap up your sightseeing on the 8th (Fri) early enough to drive to Cinque Terre.
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Historic Sites · Museums · Neighborhoods · Parks
Side Trip
Find places to stay Apr 4 — 8:

Cinque Terre — 5 nights

Italian Riviera

Made up of five picturesque towns on the Ligurian coast, Cinque Terre is Italy's answer to the French Riviera.
Step off the beaten path and head to Parco Nazionale Cinque Terre and Footpath Monterosso - Vernazza. You'll find plenty of places to visit near Cinque Terre: La Spezia (Monesteroli & Ponte Thaon di Revel) and Genoa (Basilica della Santissima Annunziata del Vastato & Aquarium of Genoa). There's much more to do: step into the grandiose world of Castello Doria, appreciate the extensive heritage of Borgo Storico di Riomaggiore, take in the architecture and atmosphere at Santa Margherita di Antiochia Church, and don't miss a visit to Borgo Antico.

To find ratings, more things to do, photos, and tourist information, you can read our Cinque Terre trip planner.

You can drive from Venice to Cinque Terre in 4.5 hours. Other options are to fly; or take a train. In April in Cinque Terre, expect temperatures between 22°C during the day and 9°C at night. Cap off your sightseeing on the 13th (Wed) early enough to go by car to Florence.
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Historic Sites · Parks · Outdoors · Trails
Side Trips
Find places to stay Apr 8 — 13:

Florence — 5 nights

Birthplace of the Italian Renaissance

Considered a cultural, artistic, and architectural jewel of Italy, Florence is the birthplace of the Italian Renaissance.
Eschew the tourist crowds and head to Centro Storico and Perseus Statue. There's lots more to do: indulge in some culinary diversions at a local gastronomic tour, take some stellar pictures from Basilica San Miniato al Monte, take in the local highlights with Walking tours, and appreciate the history behind Loggia dei Lanzi.

For where to stay, more things to do, maps, and tourist information, use the Florence trip planner.

Traveling by car from Cinque Terre to Florence takes 2.5 hours. Alternatively, you can take a train. April in Florence sees daily highs of 22°C and lows of 11°C at night. Finish your sightseeing early on the 18th (Mon) so you can drive to Volterra.
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Historic Sites · Museums · Tours · Shopping
Find places to stay Apr 13 — 18:

Volterra — 3 nights

Volterra is a walled mountaintop town in the Tuscany region of Italy of which its history dates to before the 7th century BC and has substantial structures from the Etruscan, Roman, and Medieval periods.HistoryVolterra, known to the ancient Etruscans as Velathri or Vlathri and to the Romans as Volaterrae, is a town and comune in the Tuscany region of Italy. You'll discover tucked-away gems like Palazzo dei Priori and Chiesa di San Lino. There's lots more to do: steep yourself in history at Cathedral of Santa Maria Assunta, explore the world behind art at Palazzo Viti, delve into the distant past at Roman Theatre, and make a trip to Piazza dei Priori.

Inspirock's itinerary builder makes planning a Volterra trip simple and quick.

Traveling by car from Florence to Volterra takes 1.5 hours. Alternatively, you can do a combination of train and taxi. Expect a daytime high around 22°C in April, and nighttime lows around 9°C. Finish up your sightseeing early on the 21st (Thu) so you can go by car to Siena.
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Historic Sites · Museums
Find places to stay Apr 18 — 21:

Siena — 3 nights

Cultural Heart of Tuscany

Siena, a medieval Tuscan city, features numerous attractions, including a historic town center, alleyways, towers, and well-preserved buildings.
You'll discover tucked-away gems like Centro Storico di Siena and Basilica Cateriniana San Domenico. Take a break from Siena with a short trip to Via delle Volte in Castellina In Chianti, about 44 minutes away. There's much more to do: take in panoramic vistas at Torre del Mangia, contemplate the long history of Loggia della Mercanzia, explore the historical opulence of La Rocca di Staggia, and make a trip to Via di Citta.

To see reviews, where to stay, traveler tips, and other tourist information, you can read our Siena online trip planner.

You can drive from Volterra to Siena in an hour. Alternatively, you can do a combination of taxi and train; or take a bus. Expect a daytime high around 23°C in April, and nighttime lows around 9°C. Cap off your sightseeing on the 24th (Sun) early enough to go by car to Montalcino.
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Historic Sites
Side Trips
Find places to stay Apr 21 — 24:

Montalcino — 2 nights

City of Honey

In the heart of wine country, the hill town of Montalcino offers a glimpse of untouched medieval-era Tuscany.
Start off your visit on the 24th (Sun): get to know the fascinating history of Borgo Medievale Cinto da Mura, learn about winemaking at NostraVita, and then steep yourself in history at Abbazia di Sant'Antimo. Keep things going the next day: do a tasting at Podere Il Cocco, learn about winemaking at Ciacci Piccolomini d'Aragona, and then do a tasting at Azienda Agricola Uccelliera.

To find reviews, photos, and tourist information, you can read our Montalcino journey app.

You can drive from Siena to Montalcino in an hour. Other options are to take a bus; or do a combination of train and bus. In April, daytime highs in Montalcino are 23°C, while nighttime lows are 9°C. Finish your sightseeing early on the 26th (Tue) to allow enough time to drive to Pienza.
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Wineries · Historic Sites
Side Trip
Find places to stay Apr 24 — 26:

Pienza — 2 nights

Pienza, a town and comune in the province of Siena, in the Val d'Orcia in Tuscany (central Italy), between the towns of Montepulciano and Montalcino, is the "touchstone of Renaissance urbanism."In 1996, UNESCO declared the town a World Heritage Site, and in 2004 the entire valley, the Val d'Orcia, was included on the list of UNESCO's World Cultural Landscapes.HistoryBefore the village was renamed to Pienza its name was Corsignano. On the 26th (Tue), make a trip to Corso il Rossellino, then contemplate the long history of Historic Centre of the City of Pienza, and then contemplate the long history of Terme Bagno Vignoni. Here are some ideas for day two: don't miss a visit to The Checche Oak Tree, stop by Monticchiello, stop by La Taverna del Pecorino, then see the interesting displays at Palazzo Piccolomini, and finally don't miss a visit to Piazza Pio II.

For more things to do, other places to visit, photos, and more tourist information, refer to the Pienza holiday builder.

Pienza is just a stone's throw from Montalcino. In April, plan for daily highs up to 23°C, and evening lows to 9°C. Wrap up your sightseeing on the 28th (Thu) to allow time to drive to Montepulciano.
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Historic Sites · Neighborhoods · Shopping · Museums
Side Trip
Find places to stay Apr 26 — 28:

Montepulciano — 3 nights

Pearl of the 16th Century

Perched on a limestone ridge in the heart of Tuscany, Montepulciano is known worldwide for its production of red wine, the Vino Noble.
Eschew the tourist crowds and head to Piazza Grande a Montepulciano and Duomo di Cortona. Explore the numerous day-trip ideas around Montepulciano: Cortona (Museo Diocesano & Santa Maria del Calcinaio). Next up on the itinerary: take in the spiritual surroundings of Sant'Agostino, indulge your senses at some of the top wineries in the area, get to know the fascinating history of Centro storico, and do a tasting at Gattavecchi Winery.

To find traveler tips, ratings, reviews, and other tourist information, read Montepulciano trip builder app.

Montepulciano is just a short distance from Pienza. In April in Montepulciano, expect temperatures between 23°C during the day and 9°C at night. Wrap up your sightseeing on the 1st (Sun) early enough to drive to Assisi.
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Historic Sites · Wineries · Tours · Museums
Side Trip
Find places to stay Apr 28 — May 1:

Assisi — 2 nights

City of Peace

Rich in culture and religious tradition, Assisi is known as the birthplace of St.
On the 1st (Sun), pause for some serene contemplation at Basilica Papale e Sacro Convento di San Francesco d'Assisi, explore the world behind art at Studio Moretti Caselli, then admire the striking features of San Pietro, then examine the collection at Museo della Porziuncola, and finally take in the spiritual surroundings of Eremo delle Carceri. On the next day, see the interesting displays at Museo-Laboratorio di Tessitura a Mano Giuditta Brozzetti, step into the grandiose world of Rocca Paolina, and then do a tasting at Vineria del Carmine.

To find ratings, where to stay, traveler tips, and other tourist information, refer to the Assisi sightseeing website.

Traveling by car from Montepulciano to Assisi takes 1.5 hours. Alternatively, you can take a train; or take a bus. In May, plan for daily highs up to 26°C, and evening lows to 13°C. Wrap up your sightseeing on the 3rd (Tue) early enough to drive to Orvieto.
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Museums · Historic Sites · Wineries
Side Trip
Find places to stay May 1 — 3:

Orvieto — 3 nights

Green Heart of Italy

The striking town of Orvieto, perched on a volcanic cliff overlooking the Umbrian countryside, is known as the Green Heart of Italy.
You'll explore the less-touristy side of things at Duomo di Orvieto and Madonna del Latte. You'll find plenty of places to visit near Orvieto: Culture Discovery Vacations - Cooking Classes & Vacations (in Soriano nel Cimino), Santuario dell'Amore Misericordioso (in Collevalenza) and La Corsa All'anello - San Giovenale (in Narni). There's more to do: take in panoramic vistas at Torre del Moro and learn about winemaking at Decugnano dei Barbi.

To find other places to visit and other tourist information, refer to the Orvieto holiday website.

Drive from Assisi to Orvieto in 1.5 hours. Alternatively, you can take a train; or take a bus. Expect a daytime high around 25°C in May, and nighttime lows around 12°C. Finish your sightseeing early on the 6th (Fri) so you can drive to Rome.
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Wineries · Tours · Historic Sites
Side Trips
Find places to stay May 3 — 6:

Rome — 5 nights

Eternal City

Aptly nicknamed the Eternal City, Rome is the birthplace of the Roman Empire, one of the world's greatest civilizations ever.
Discover out-of-the-way places like Welcome To Rome and Wine Tours & Tastings. Next up on the itinerary: steep yourself in history at Colosseum, admire the masterpieces at Vatican Museums, contemplate in the serene atmosphere at Cupola di San Pietro, and admire the striking features of Villa Borghese.

To find other places to visit, where to stay, photos, and tourist information, you can read our Rome trip itinerary maker site.

You can drive from Orvieto to Rome in 2 hours. Alternatively, you can take a train; or take a bus. Traveling from Orvieto in May, you can expect nighttime temperatures to be a bit warmer in Rome, with lows of 17°C. Finish up your sightseeing early on the 11th (Wed) so you can catch the train to Sorrento.
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Historic Sites · Tours · Wineries · Museums
Side Trip
Find places to stay May 5 — 11:

Sorrento — 4 nights

Land of the Sirens

A lovely town easily accessible from almost anywhere in the country, Sorrento overlooks the Bay of Naples and sits right on the Amalfi Drive.
Discover out-of-the-way places like Il Sentiero Degli Dei and Villa Comunale. Explore the numerous day-trip ideas around Sorrento: Villa Rufolo (in Ravello), Positano (Boat Tours & Water Sports & Church of Santa Maria Assunta) and Amalfi (Antichi Sapori d'Amalfi, Duomo di Sant'Andrea, &more). There's much more to do: make a trip to Piazza Tasso, explore the ancient world of Odeon - Teatro Piccolo, take in the local highlights with Walking tours, and contemplate in the serene atmosphere at Basilica di Sant'Antonino.

To see traveler tips, maps, other places to visit, and more tourist information, use the Sorrento trip planner.

You can take a train from Rome to Sorrento in 3 hours. Alternatively, you can drive; or take a bus. May in Sorrento sees daily highs of 27°C and lows of 18°C at night.
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Historic Sites · Tours · Parks · Outdoors
Side Trips
Find places to stay May 11 — 15:

Italy travel guide

4.6
Landmarks · Ruins · Beaches
Italy is a land of high fashion, fine art, exquisite architecture, luxury sports cars, outstanding cuisine--and an insatiable taste for "la dolce vita." It's also home to the greatest number of World Heritage Sites in the world, making it an ideal place for your next holiday. The country boasts a varied landscape of mountain ranges, alpine lakes, and coastal towns, so it's no wonder travelers often refer to it as the bel paese (beautiful country). With so many places to visit, visitors often have a difficult time planning their itinerary. The smaller villages each feature a distinct character and a blend of architecture, art, and cuisine. In the country, you'll find countless archeological sites dating back to Roman times and beyond. The country's cities and seaside resorts are cosmopolitan powerhouses with museums, galleries, restaurants, shops, open-air markets, and pedestrian-friendly historic areas.
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