16 days in Italy Itinerary

16 days in Italy Itinerary

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Route & dates

16 days in Italy Itinerary

Start: New York City
Bus + Fly:  11 h 30 min
1
Venice
— 2 nights
Fly:  3 h 15 min
2
Rome
— 3 nights
Train + Subway:  3 h
3
Amalfi
— 3 nights
Drive:  4 h 30 min
4
Assisi
— 2 nights
Drive:  2 h 15 min
5
Florence
— 3 nights
Train:  1 h 45 min
6
Milan
— 1 night
Fly:  12 h 30 min
End: New York City

2
nights
Venice

Venice ©
Virtually unchanged for the last six centuries, Venice is actually a group of islands made famous by a series of canals, bridges, monuments, piazzas, and narrow pedestrian lanes.
Change things up with a short trip to Scrovegni Chapel in Padua (about 54 minutes away). There's still lots to do: contemplate the waterfront views at Canal Grande, snap pictures at Ponte di Rialto, admire the striking features of Basilica di San Marco, and admire the masterpieces at Gallerie dell'Accademia.

To see where to stay, other places to visit, reviews, and tourist information, read our Venice day trip planning app.

New York City, USA to Venice is an approximately 11.5- hour combination of bus and flight. You can also fly; or do a combination of train and flight. The time zone difference when traveling from New York City to Venice is 6 hours. April in Venice sees daily highs of 65°F and lows of 49°F at night. Finish up your sightseeing early on the 10th (Fri) so you can travel to Rome.

Things to do in Venice

Historic Sites Museums Nature

Side Trip

Scrovegni Chapel
Find places to stay Apr 7 — 10:
Highlights from your plan
Canal Grande ©
Canal Grande
Doge's Palace ©
Doge's Palace
Basilica di San Marco
Basilica di San Marco

3
nights
Rome

Rome ©
Aptly nicknamed the Eternal City, Rome is the birthplace of the Roman Empire, one of the world's greatest civilizations ever.
Rome is known for historic sites, nightlife, and museums. Your plan includes some of its best attractions: steep yourself in history at Colosseum, explore the world behind art at Galleria Borghese, make a trip to Spanish Steps, and explore the ancient world of Palatine Hill.

For other places to visit, photos, reviews, and more tourist information, you can read our Rome trip planner.

You can fly from Venice to Rome in 3.5 hours. Alternatively, you can take a train; or drive. In April, daytime highs in Rome are 69°F, while nighttime lows are 49°F. Wrap up your sightseeing on the 13th (Mon) early enough to travel to Amalfi.

Things to do in Rome

Historic Sites Museums Neighborhoods

Side Trip

Vatican City
Find places to stay Apr 10 — 13:
Highlights from your plan
Colosseum ©
Colosseum
Pantheon ©
Pantheon
Trevi Fountain ©
Trevi Fountain

3
nights
Amalfi

Amalfi ©
Known for its impressive hillside cascade of colorful stone buildings down to the Mediterranean shore, Amalfi is the cultural and commercial heart of southern Italy's Amalfi Coast.
Explore the numerous day-trip ideas around Amalfi: Praiano (I Suoni degli Dei - Pelagos & Cappella Madonna di Costantinopoli). There's still lots to do: make a trip to Villa Rufolo, get to know the fascinating history of Centro Storico, explore the fascinating underground world of Grotte di Suppraiano, and take in the architecture and atmosphere at Cappella Sant'Angelo all'Ospedale.

To find out how to plan a trip to Amalfi, use our trip itinerary maker.

You can do a combination of train and subway from Rome to Amalfi in 3 hours. Other options are to drive; or do a combination of train and bus. Expect a bit warmer evenings in Amalfi when traveling from Rome in April, with lows around 59°F. Wrap up your sightseeing on the 16th (Thu) early enough to drive to Assisi.

Things to do in Amalfi

Historic Sites Parks Outdoors

Side Trips

Praiano, Ravello, Maiori
Find places to stay Apr 13 — 16:
Highlights from your plan
Villa Rufolo ©
Villa Rufolo
I Suoni degli Dei - Pelagos ©
I Suoni degli Dei - Pelagos
Villa Cimbrone Gardens ©
Villa Cimbrone Gardens

2
nights
Assisi

Assisi ©
Rich in culture and religious tradition, Assisi is known as the birthplace of St.
Kick off your visit on the 17th (Fri): steep yourself in history at San Damiano, do a tasting at Bibenda Assisi, get to know the fascinating history of Centro Storico di Assisi, then pause for some serene contemplation at Basilica Papale e Sacro Convento di San Francesco d'Assisi, and finally get to know the fascinating history of Piazza Superiore di San Francesco. Here are some ideas for day two: step into the grandiose world of Rocca Maggiore, take in the spiritual surroundings of Eremo delle Carceri, do a tasting at Azienda Agraria Saio, then see the interesting displays at Museo della Porziuncola, then do a tasting at Tili Vini Societa Agricola, and finally stroll around Mount Subasio.

For maps, ratings, more things to do, and other tourist information, go to the Assisi trip planner.

You can drive from Amalfi to Assisi in 4.5 hours. Other options are to take a train; or do a combination of bus and train. Traveling from Amalfi in April, expect slightly colder with lows of 45°F in Assisi. Wrap up your sightseeing on the 18th (Sat) early enough to drive to Florence.

Things to do in Assisi

Historic Sites Wineries Museums
Find places to stay Apr 16 — 18:
Highlights from your plan
Azienda Agraria Saio ©
Azienda Agraria Saio
Tili Vini Societa Agricola ©
Tili Vini Societa Agricola

3
nights
Florence

Florence ©
Considered a cultural, artistic, and architectural jewel of Italy, Florence is the birthplace of the Italian Renaissance.
Florence is known for museums, historic sites, and shopping. Your plan includes some of its best attractions: explore the world behind art at Academy Of Florence Art Gallery, contemplate in the serene atmosphere at Cathedral of Santa Maria del Fiore, contemplate the long history of Basilica of Santa Croce, and examine the collection at Pitti Palace.

To see other places to visit, where to stay, more things to do, and other tourist information, use the Florence trip itinerary builder site.

Traveling by car from Assisi to Florence takes 2.5 hours. Alternatively, you can take a train. Expect a daytime high around 67°F in April, and nighttime lows around 50°F. Wrap up your sightseeing on the 21st (Tue) early enough to take a train to Milan.

Things to do in Florence

Historic Sites Museums Shopping
Find places to stay Apr 18 — 21:
Highlights from your plan
Art Gallery Studio Iguarnieri ©
Art Gallery Studio Iguarnieri
Academy Of Florence Art Gallery ©
Academy Of Florence Art Gallery
Piazzale Michelangelo ©
Piazzale Michelangelo

1
night
Milan

Milan ©
In many ways the most modern of Italian cities, Milan is a busy, elegant metropolis with an impressive list of grand palaces, fine churches, and important museums.
Start off your visit on the 22nd (Wed): admire the masterpieces at Pinacoteca Ambrosiana, contemplate in the serene atmosphere at Duomo di Milano, and then admire the striking features of Galleria Vittorio Emanuele II.

Plan a trip to Milan easily and quickly by telling Inspirock to suggest an itinerary.

You can take a train from Florence to Milan in 2 hours. Alternatively, you can drive; or fly. Expect a daytime high around 66°F in April, and nighttime lows around 46°F. Cap off your sightseeing on the 22nd (Wed) early enough to travel back home.

Things to do in Milan

Museums Historic Sites Shopping
Find places to stay Apr 21 — 22:
Highlights from your plan
Duomo di Milano ©
Duomo di Milano
Galleria Vittorio Emanuele II ©
Galleria Vittorio Emanuele II
Pinacoteca Ambrosiana ©
Pinacoteca Ambrosiana

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